CST1 and asthma: The level of CST1 in the bronchial epithelium of AR comorbid asthma was significantly increased compared to AR alone, while no significant difference was observed in the nasal epithelium between AR comorbid asthma and AR alone, which was further confirmed by GSE19187 dataset, in which AR alone and AR comorbid asthma (controlled or not controlled) presented similar CST1 expression level in the nasal epithelium (Figure 5C).