Further, after 3 months of doxorubicin therapy, the downstream protein expression of MyD88 and NF-κB was significantly higher in the Dox-HF group (MyD88, 0.78 ± 0.07; NF-κB, 2.87 ± 0.18) than in the Dox-baseline group (MyD88, 0.39 ± 0.04; NF-κB, 1.58 ± 0.14). This evidence concerns the gene NFKB1 and hydrops fetalis.