By comparison of major monocyte subsets in patients with colon and rectal cancers, statistically significant decrease in the percentage of CD14-16+ monocytes was found in patients with colon cancer compared to rectal cancer (5,94 (3,38–7,6) vs. 3,62 (1,72–7,28), p=0,04) (Table 1). This evidence concerns the gene CD14 and malignant colon neoplasm.