Supplementation with the functional food HI-MAIZE® 260 cookies (16 g/d resistant starch) could increase fiber intake, reduce IL-6 and IS plasma levels (Esgalhado et al., 2018), decrease different growth factors (De Paiva et al., 2020), and alter the SCFA-producing microbiota in HD patients (Kemp et al., 2021), but no indole-3-acetic acid (IAA) levels or aryl hydrocarbon receptor (AhR) expression in patients with end-stage CKD (Azevedo et al., 2020). This evidence concerns the gene AHR and Huntington disease.