STAT3 and Miyoshi myopathy: The significance of assessment of neutrophil CD64 expression as a potential diagnostic tool is corroborated by previous observations demonstrating elevated STAT3 signaling and expression of CD64 on neutrophils from MGUS and MM patients and an association between upregulated CD64 and disease progression in MM patients treated with bortezomib, thalidomide, and dexamethasone (9, 75).