YTHDF1 and esophageal squamous cell carcinoma: Through Venn diagrams, the m6A regulators significantly related to ESCC screened in our RNA-seq data and TCGA-ESCA database based on machine learning were overlapped, and then the final ESCC related m6A regulators in this study were screened: YTHDF1 and HNRNPC (Figure 4A).