In these modules, the expression levels of module genes except PSMB1, KARS, TERT, ZBTB16, NFKB1, MAPKAPK2, MAP3K3, MAP2K4, IRS2, IQGAP1, HDAC1, EPB41L3, C1QBP, BRCA1, BAG2, FYN, MAPK6, MAP3K2, and FNY in the PD group were higher than that in the control group. This evidence concerns the gene MAP2K4 and Parkinson disease.