In these modules, the expression levels of module genes except PSMB1, KARS, TERT, ZBTB16, NFKB1, MAPKAPK2, MAP3K3, MAP2K4, IRS2, IQGAP1, HDAC1, EPB41L3, C1QBP, BRCA1, BAG2, FYN, MAPK6, MAP3K2, and FNY in the PD group were higher than that in the control group. The gene discussed is MAPKAPK2; the disease is Parkinson disease.