IL27 and autoimmune disease: Several SNPs (rs12126142 for IL-6ra, rs4959106 for IL-6, rs6734238 for IL-1ra, and rs10774624 for IL-27) were related with other phenotypes at the genome-wide significance level, containing smoking, height, body mass, high cholesterol, different fibrinogen levels, white blood cells and other autoimmune diseases (Supplementary Table 8).