By using multivariable multinomial logistic regression analysis, when DM was considered as the independent variable, LDL-C per 10 (OR = 1.122, 95%CI 1.019–1.235, p = 0.019) and VEGF-D per100 (OR = 1.674, 95%CI 1.053–2.661, p = 0.029) were significantly different between the DR and DM group (Figure 3). This evidence concerns the gene VEGFD and diabetes mellitus.