In humans, single de novo missense mutations in KIF2A were found in patients with early-life epilepsy, posterior pachygyria, microcephaly, and partial agenesis of corpus callosum (Poirier et al., 2013; Tian et al., 2016; Cavallin et al., 2017; Hatano et al., 2021). Here, KIF2A is linked to epilepsy.