Thus, the purpose of the present study was to investigate the presence of Pg DNA in the oral cavity and blood samples of patients with acute myocardial infarction (AMI) and non-CHD patients, and analyze its relationship with the incidence of AMI, inflammatory markers, and severity of coronary artery disease, with the aim to optimize early risk stratification for CHD patients and guide clinical treatment. This evidence concerns the gene JUP and coronary artery disorder.