We leveraged the integrated immune PBMC atlas to map IFN-β dataset (as in Fig. 2a) and a new dataset from two patients (P1 and P2) at different COVID stages (severe disease and during the remission process: D1, severe COVID-19 on day 1; D5 and D7, remission on days 5 and 7, respectively). This evidence concerns the gene IFNB1 and COVID-19.