DKC1 and metastatic neoplasm: We have explored the expression of sncRNAs in cSCC samples from patients with non-metastatic and metastatic tumors, and we have observed the reduced expression of a specific subset of sncRNAs, the H/ACA snoRNAs, whereas the number of lymph metastasis expressing DKC1, the core protein with enzymatic activity of the H/ACA RNPs, is lower than DKC1-positive primary tumors.