Among 27 different mediators tested, only the secretion levels of interleukin (IL)-6, IL-8, IP-10, and Granulocyte colony stimulating factor (G-CSF) were significantly increased by EBOV infection at day 2 (p < 0.05, or p < 0.0001) post infection when a high infective dose was used (Fig. 6). This evidence concerns the gene IL6 and infection.