For the similar reason, PSA reduction ratio at 6 months (PSA 6months/Pre-operative PSA) after surgery was not significantly different between IPCa and BPH patients (IPCa 0.33 [0.22, 0.58] vs BPH 0.29 [0.16, 0.57], p = 0.091). This evidence concerns the gene KLK3 and benign prostatic hyperplasia.