IGF1 and acne: Elevations of plasma GH and IGF-1 concentrations by cow’s milk intake may thus enhance the physiological magnitude of circulating GH/IGF-1 during puberty deviating sebaceous gland, eye growth, and bone homeostasis (displaying acne, early-onset juvenile myopia, pubertal skeletal overgrowth) but indiscernibly disturbing mammary gland maturation and TEB formation potentially increasing the risk of BCa.