In Cohort 6 (BA9, depression vs control, n = 34), FKBP5 gex expression was + 24.8% higher in depression in the excitatory neuron group, although this did not survive correction for multiple cluster comparisons (t =  – 2.327, P = 0.0267, FDR = 0.187; Fig. 4d, ii; Online Resource, Supplementary Table 13 and Supplementary Fig. 3). This evidence concerns the gene FKBP5 and depressive disorder.