In the superficial layers, there was no difference in the number of FKBP5+ NeuN+ neurons in schizophrenia or depression, but there was an increase in bipolar disorder vs controls (+ 10% mean difference; t = 10.683, P = 2.00E-16, FDR = 3.00E-16, Fig. 4e, i). This evidence concerns the gene RBFOX3 and bipolar disorder.