AR and posterior cortical atrophy: A dataset of 22 PCa PDX models showed H3K27ac peaks more frequently in AR upstream enhancer (20/22) than AR intron 3 enhancer (7/22) (Supplementary Figure S5A), while another dataset of 22 PCa organoid models showed ATAC-seq peaks more frequently in AR intron 3 enhancer (12/22) than AR upstream enhancer (2/22) (Supplementary Figure S5B).