have shown that the expression of circ-RanGAP1(hsa_circ_0063526) is high in GC exosomes and promotes the progression of GC through the miR-877-3p/VEGFA axis (66).Gao and coworkers have reported that circCOG2(hsa_circ_0016866) in the exosomes of colon cancer cells promotes CRC progression by sponging miR-1305 to promote the proliferation, migration, and invasion of CRC (67). This evidence concerns the gene VEGFA and colorectal carcinoma.