CLOCK and neuromyelitis optica: Moreover, the mRNA expression level of Bmal1 and Clock (Figure 5B) and the glutamate levels (Figure 5C) were also suppressed by Bmal1 knockdown, which was neither changed by the treatment of TAT-Gap19 and DQP-1105 in normal astrocytes nor the treatment of LA or glutamate treatment in NMO astrocytes.