Autoimmune labs (ANA, c-ANCA, p-ANCA, RA factor), inflammatory markers like ESR and CRP, immunoglobulin assessment, immunophenotyping, and organ-specific markers like serum creatinine, proteinuria, liver enzymes, and thyroid function tests should be obtained for a baseline and assessment of therapy response. The gene discussed is PRTN3; the disease is rheumatoid arthritis.