Moreover, increased lTSLP expression was correlated with DAS28 and ESR, which are reliable biochemical indicators of the acute phase reaction in RA, yet not with other laboratory parameters including RF, CRP, C3, C4, IgG, IgA, IgM, Anti-CCP, Anu A, Anti-dsDNA, and G6PI. This evidence concerns the gene C3 and rheumatoid arthritis.