IL1B and rheumatoid arthritis: We cultured PBMCs from different cohorts in the presence or absence of lTSLP under LPS treatment to discern the pro- and anti-inflammatory cytokine expression and revealed that the mRNA expression of cytokines IL-1β, IL-6, IL-8, and IL-10 was upregulated in response to LPS in PBMCs of RA patients and healthy subjects.