It has been widely reported that the elevation of proinflammatory cytokines (IL-1β, IL-6, and IL-8) could promote immune cells to migrate to inflammation sites and take part in the progression of RA inflammation (4, 31), indicating the potentially harmful effects of lTSLP in aggravating the disease situation of patients with RA. This evidence concerns the gene CXCL8 and rheumatoid arthritis.