Most of these genes, including DBI (45), FYN (46), IL18 (47), CDK1 (48), RPS3 (49), PDCD1LG2 (50), FADD (51), CXCL12 (52), CLIC1 (53), CDK2 (54), IGFBP2 (55) and LRRC32 (56), have been reported to play critical roles in the development, stemness, and immunogenicity of gliomas. This evidence concerns the gene LRRC32 and central nervous system cancer.