The tissue-enriched genes (TEGs) of subtype 2 were the most correlated with the development of cancer (allograft rejection, coagulation, and epithelial-mesenchymal transition) and immune-related pathways (inflammatory response, interferon alpha/gamma response, and TNF signaling via NFκB; Figure S1A) as opposed to those of subtype 1. This evidence concerns the gene TNF and cancer.