The main pathways of enrichment included lipid and atherosclerosis, Kaposi's sarcoma-associated herpesvirus infection, human cytomegalovirus infection, hepatitis B, fluid shear stress and atherosclerosis, pathways of neurodegeneration-multiple diseases, PI3K/Akt signaling pathway, MAPK signaling pathway, chemical carcinogenesis-receptor activation, and human T-cell leukemia virus 1 infection (Figure 2(d)). The gene discussed is AKT1; the disease is atherosclerosis.