The process of NSCLC development is complex and diverse, involving multiple signaling pathways, such as PI3K/Akt signaling pathway, human matrix metalloproteinase 9 (MMP9), cell cycle protein-dependent kinase 1 (CDK1), and Wnt/β-catenin signaling pathway [3–6]. The gene discussed is MMP9; the disease is non-small cell lung carcinoma.