The results showed the highest enrichment in tumor-related signaling pathway (target number 15), lipid and atherosclerosis signaling pathway (target number 10), PI3K-Akt signaling pathway (target number 10), and neurodegenerative signaling pathway (target number 10), indicating that Citrus aurantium can treat NSCLC through these pathways. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.