Among them, ILL (70 in Table 1) is the most representative, and it acts on different cancers through different pathways (Figure 8): it can induce apoptosis of human OC cells by increasing the production of mitochondrial superoxide, decreasing the expression of mitochondrial SOD2, and interfering with the signal transducer and activator of transcription 3 (STAT3)-mediated signaling pathway (29). The gene discussed is STAT3; the disease is cancer.