IFNA1 and systemic lupus erythematosus: Similar to the pristine induced lupus model, cutaneous administration of the TLR7 agonist Imiquimod in different strains of wild-type mice induced pDC-driven lupus-like disease with glomerulonephritis, autoantibodies, and increased expression of the IFN regulated genes Mx1 and IFna (Yokogawa et al., 2014).