For example, a missense SNP (rs13107325) the zinc transporter SLC39A8 influences the risks of at least seven different diseases and genetic traits, including schizophrenia, Parkinson’s disease, Crohn’s disease, allergy, height, nearsightedness, and HDL (Pickrell et al., 2016); and SNPs in the TERT-CLPTM1L locus have been associated with more than 12 different cancer and non-cancer diseases (Tian et al., 2022). Here, TERT is linked to Crohn disease.