Several SNPs in MEG3 have been reported in literature that may affect MEG3 expression and influence the risks of various diseases including inflammatory response, diabetes, stroke, and cancer (Wallace et al., 2010; Han et al., 2018; Ghaedi et al., 2018; Ghafouri-Fard & Taheri, 2019; Gao et al., 2021; Zhu et al., 2021; Zhong et al., 2022). The gene discussed is MEG3; the disease is cancer.