AKT1 and asthma: MEG3 also contributes to the regulation of several other important cellular signaling pathways, including PI3K/AKT/mTOR, Wnt/β-catenin, JAK/STAT, and Notch, and these pathways have been implicated in asthma (Wang et al., 2014; Ghafouri-Fard & Taheri, 2019; Athari, 2019; Zhao et al., 2020.