Our results also point out genes with emerging cancer-related roles outside of classical cancer pathways such as GSTM1/GSTT1 in xenobiotic metabolism (Ginsberg et al., 2009), ELF2 as an ETS transcription factor regulating various biological pathways (Seth and Watson, 2005) or DLC1 as a Rho-GTPase activating protein regulating RhoA pathway in hepatocellular carcinoma (Xue et al., 2008). The gene discussed is RHOA; the disease is hepatocellular carcinoma.