The key pathways implicated in ginseng against AD were hsa04080 (neuroactive ligand-receptor interaction), hsa04020 (calcium signaling pathway), hsa04151 (PI3K-Akt signaling pathway), hsa04726 (serotonergic synapse), hsa04024 (cAMP signaling pathway), hsa04014 (Ras signaling pathway), hsa04015 (Rap1 signaling pathway), and hsa04068 (FoxO signaling pathway). This evidence concerns the gene AKT1 and Alzheimer disease.