Lymphoma subjects with extranodal involvement had higher PD-L1+CXCR3+% and PD-1+CXCR3+% compared with subjects without extranodal involvement (median 65% vs. 4%; 12.2% vs. 2%, P < 0.001, respectively) (Figures 1(a)–1(d)). The gene discussed is CXCR3; the disease is lymphoma.