In multivariate COX regression analysis, higher HbA1c was still associated with higher risk of hypertension after adjusting for age, sex, educational level, marital status, smoking status, drinking status, diabetes, hypoglycemic drugs, BMI, SBP, DBP, TG, TC, LDL-C, ApoB, CR, uric acid, FPG and Hs-CRP (HR: 1.102, 95% CI: 1.006-1.206, P = 0.037). The gene discussed is APOB; the disease is diabetes mellitus.