As shown in Table 2, HbA1c was associated with the risk of hypertension in univariate COX regression analysis (HR: 1.161, 95% CI: 1.105-1.221, P < 0.001), and age, sex, educational level, smoking status, drinking status, diabetes, hypoglycemic drugs, BMI, SBP, DBP, TG, TC, LDL-C, ApoB, CR, uric acid, FPG and Hs-CRP were also associated with the risk of hypertension (P < 0.05). The gene discussed is APOB; the disease is diabetes mellitus.