In addition, we conducted ten times 10-fold cross-validation experiments on bSRWPSO-FKNN based on a specific medical dataset in this paper and successfully extracted the key features affecting the onset of AD, mainly including the content of lymphocytes (LY), Cat dander, Milk, Dermatophagoides Pteronyssinus/Farinae, Ragweed, Cod and Total IgE. This evidence concerns the gene IGHE and Alzheimer disease.