Apart from hydrocortisone, several studies have tested the use of different immunomodulatory molecules for hemorrhagic shock and sepsis in animal models or even in humans—including granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF), IFN-γ, intravenous immunoglobulins, IL-10, TGF-β, IL-7, Thymosin α1, and others (Thompson et al., 2019). This evidence concerns the gene IL10 and Sepsis.