SGLT2 inhibitorscan be continued until an eGFR of 15 mL/min/m2 or the start ofdialysis (see Question 3, 4, and 6).6,7,121 Empagliflozin isindicated for treatment of HF with SGLT2 inhibitor initiation at eGFRs ≥20mL/min/m2. The gene discussed is SLC5A2; the disease is hydrops fetalis.