Zhang Fanfan et al. [23] have found that the APO-B/APO-A1 level of GDM pregnant women was greater than that of non-GDM pregnant women, and APO-B/APO-A1 combined with HOMA-IR had a high predictive value for adverse pregnancy outcomes such as macrosomia. The gene discussed is APOA1; the disease is Large for gestational age.