A variant in HMGN5, rs185387095, was a top suggested association in this study, and a nearby variant in rs142755000 in linkage disequilibrium was also suggested; rs142755000 was identified in association with FEV1 in prior whole genome sequence analysis of COPD-enriched White race populations including COPDGene [17]. This evidence concerns the gene HMGN5 and chronic obstructive pulmonary disease.