Chen et al. [7] indicated that through the microarray and RNA-sequencing conducted on healthy donor and patients with severe asthma, miR-133a-3p-EFHD2/CNN2-AC144831.1 interactions and miR-3613-3p-CD44/BCL11B-LINC00158/CTA-217C2.1/AC010976.2/RP11-641A6.2 interactions were speculated to involve with the development of severe asthma. The gene discussed is CD44; the disease is asthma.