MGMT and glioblastoma: Parsing glioblastoma samples by MGMT methylation status (a prognostic indicator) unveiled minimal immunological differences; however, subdivision by survival time revealed a higher endothelial frequency in tumours from long-term survivors (LTSs) (overall survival more than three years) compared with those from short-term survivors (STSs) (overall survival less than one year) (Fig. 2a).