A previous study in which TCGA–BRCA ATAC-seq data were reanalysed revealed that the FOXA1 motif was more enriched in ER + /HER2 − invasive ductal carcinoma (IDC) tumours than in ER + /HER2 − invasive lobular carcinoma (ILC) tumours [26]. Here, ESR1 is linked to invasive ductal breast carcinoma.