EXOC7 AS switches have been previously reported to occur during EMT in breast cancer [43]; one isoform containing an alternative 3 ́ region of exon 8 (isoform 5 or E) promotes a non-invasive epithelial phenotype, while another isoform lacking this region (isoform 2 or M) has been associated with a mesenchymal aggressive phenotype [43]. The gene discussed is EXOC7; the disease is breast cancer.