The numbers of metabolic syndrome components were 2.6 ± 1.1 in the NH-NO group, 3.8 ± 1.1 in the NH-O group, 2.6 ± 1.1 in the LH-NO group, and 3.2 ± 1.2 in the LH-O group, respectively (Fig. 1, P < 0.001). This evidence concerns the gene PLOD1 and metabolic syndrome.