COL8A1 and neoplasm: Given that CAFs are reported to be an important stromal component and are critically involved in tumor progression,[26] we reclustered the CAFs and further categorized them into two main types (Figure 2L): inflammatory CAFs (iCAFs; CFD, CKB, and DPT) and myoblastic CAFs (myCAFs; INHBA, SULF1, and COL8A1).