We chose to knock out the magnesium transporter MAGT1/SLC58A1, known to be mutated in patients with a disorder called X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia (XMEN) (Ravell et al, 2020). This evidence concerns the gene MAGT1 and X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia.