First, the expression of CD45 (PTPRC), which is a marker for all hematopoietic cells except mature erythrocytes and platelets was observed in all three cell subsets in Lung scRNA data, while in CRC and in Melanoma scRNA datasets it was mostly seen in CD68+CD163+ cells, lower in CD68−CD163+ and absent in CD68+CD163− (Data not shown). Here, PTPRC is linked to colorectal carcinoma.