LPL and pancreatic insulinoma: A recent study has revealed that fenofibrate ameliorates lipotoxicity-induced β-cell disfunction and apoptosis in lipoprotein lipase (LPL)+/– mice and palmitate (PA)-treated stable mouse insulinoma 6 (MIN6) cells, which is achieved by the inhibition of NF-κB/MIF (macrophage-inhibitory factor) inflammatory pathway [28].