MAPK8 and acute respiratory distress syndrome: The oxidative stress markers in lung tissues, inflammatory factors in serum, cell count and neutrophil levels in BALF, and the Nrf2/HO-1 and JNK/NF-κB signaling pathways-related proteins’ levels were identified by immunofluorescence staining and western blotting to further explore the potential mechanisms of SIV effects in the ALI rats.