MFN2 and neuropathy: Most neuropathy-associated MFN2 mutations are located within the protein’s GTPase domain (Kijima et al., 2005; Züchner et al., 2004; Feely et al., 2011; Stuppia et al., 2015), but to date, all patients with MFN2-associated multiple symmetric lipomatosis (MSL) have had at least one R707W allele.