MFN2 and multiple symmetric lipomatosis: The signature of epithelial-mesenchymal transition (EMT) was the most strongly down-regulated set in mouse BAT and WAT (Figure 4I, Figure 4—figure supplement 5C, F), and was also previously found to be downregulated in overgrown human WAT in MFN2-associated multiple symmetric lipomatosis (Rocha et al., 2017).