ADSL and osteomyelitis: In vitro studies of mature AMPs must be conducted in vivo to enable the clinical advancement of peptides.[8] The in vivo experimental models of AMPs can be divided into four main categories: abdominal infection model represented by peritonitis, skin infection model represented by skin scratches, eye infection model represented by keratitis, and other infection models represented by osteomyelitis and lung infection (Figure1).