The T-cell subtype, also mainly containing GBM samples, was characterized by highest immune score, the presence of CD4 + T cell, Th1 cell, Th2 cell, etc., increased expression of the immune evasion markers PD-L1, CD70 (Wilcoxon test, p < 0.05) (Fig. 7A, E). This evidence concerns the gene CD4 and glioblastoma.